Yes, these are all bad, I know, but my game was a solid 40 FPS without too many issues on Windows 7 and seemed pretty decent at the beginning on Windows 10. My mod list is basically all graphics and cut content mods and whatever weather mod I'm trying out to make it not freeze but still have a good weather mod (Nevada Skies of late). I've even tried the old launcher and that didn't work, either. The most curious thing to me is that memory usage is always at about 2GB when it happens, which sounds like the game's limit if I didn't have the 4GB patcher, which I do. I can usually even Alt-F4 the game, at least after some of my most recent changes (but before that, it was Task Manager). My FPS is now massive and everything is phenomenally smooth, so much more than I've had it probably ever, and still, between fifteen minutes and an hour or so, it will freeze. ini files, making a load of changes using W10Privacy.and I just can't fix it. ini edits in NVSR and NVSE as well as the game's three. I have gone to the point of testing vanilla, using Process Lasso to restrict cores and raise NV's priority, overclocking my CPU and GPU, hours upon hours of testing.

Not sure that it's the same problem, though. It crashed a lot at that point, and after some changes the crashes became freezes. I've been having this problem since I forget what major Windows 10 update some months back but I have to way to know the update was the cause. The game doesn't feel as nice now but it's not crashing anymore. EDIT: The FCU Windows 10 update breaks the bHookCriticalSections setting in NVSR.

Fallout new vegas freezes